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Precise, powerful but easy-to-use cryosurgery instruments that disperse micro fine jets of nitrous oxide to permanently remove skin lesions.
It is a bloodless, stress & pain free treatment that produce great results.

What is cryosurgery?

Cryosurgery is a process to rapidly freeze skin tissue to destroy it. It has been used successfully for nearly a century.

CryoPen is an innovative cryosurgery instrument that makes treatments incredibly easy & precise. For your patient this means, no pain, no damage to surrounding healthy tissue, no unsightly scars and no aftercare required.

How does it work?

CryoPen is a pen-like device that uses a powerful microjet of cold gas to freeze skin tissue to – 89°C. You as the Medical practitioner or Veterinarian Surgeon, simple presses a trigger, and sprays cold gas for 2- 45 seconds, depending on the lesion. Only the sprayed tissue will freeze. Surrounding skin is unaffected. Frozen tissue will form a scab that will fall off and disappear in a couple of weeks.

Is cryosurgery suitable for your patients?

If your patient has an unsightly or annoying lesion that he/she like to get rid of, he/she can ask you as the Medical Practitioner to check it out and ask you about treatment option.

CryoPen can remove most common lesions easily and quickly. Such as skin tags, common warts, plantar warts, haemangioma, solar lentigo, pigmented spots, genital warts, molluscum contagiosum, actinic or seborrheic keratoses, etc. There should be no scarring, although it is possible that hair may not regrow over treated areas.

What medical markets can use a Cryopen with great success?

  • Any type of medical market, such as GP’s, Dermatologists, Gynaecologists, Aesthetic Doctors, Dental market: dentists, maxilla facial surgeons, periodontists, Oncologists, General Surgeons Podiatrists and many more.
  • Veterinarian market

Photos of lesions treated in medical market:

Above are only 2 examples, but there are 100’s of skin lesions that can be treated with enormous effectiveness.

What happens during a Cryopen treatment?


You as the treatment practitioner will examine the growth or the lesion and decide if it is safe to treat with Cryosurgery.


Treatment can be carried out by a medical professional.

No anaesthetic is needed. The practitioner will:

  • assess the size and depth of the lesion
  • point the pen at the lesion
  • press the trigger to release the gas, “painting” it over the skin for 5–30 seconds. You’ll see what looks like a white foam – it’s ice!
  • stop, wipe, then “paint” the skin again.

That’s it! In the following days, frozen tissue will crust over, forming a scab that will fall off in a week or two.


No after-treatment is required. As with any scab, avoid further irritation and use sunscreen until it has healed.

For larger or deeper lesions, a follow up visit to the doctor will be wise, to check it has healed.






NOTICE OF WARNING – CryoPen cartridges

It has been brought to our attention that a few clients who are using the CryoPEN have been using cartridges that are not manufactured by H & O Equipments, the manufacturers of the CryoPEN.

Please note that the use of any other cartridge other than the CryoPEN cartridge will

  1. Damage the CryoPEN
  2. Render the CryoPEN warranty as null and void. Any damage discovered through the use of a non CryoPEN cartridge will not be repaired by the manufacturer.

We are further advised that there are non- SAHPRA (South African Health Products Regulatory Authority) registered or licenced companies offering Cryotherapy devices and consumables.

Please note that these non- SAHPRA (South African Health Products Regulatory Authority) vendors are operating illegally in terms of the SAHPRA (ex MCC Act110) and that the purchaser of any products from such a vendor will have no claim or recourse in the event of a product failure or patient incident.

If you are approached by a non registered or licenced vendor offering any Cryotherapy equipment or supplies, please advise Sere-med, who will report them to the SAHPRA legal department.

Sere-med will continue to support our products and offer continued training and advise on the most beneficial use of our products.

Thank you for your loyal and continued support.